Graduated from Graduated from The National Academy for Theatre and Film Arts "Kr. Sarafov" (NATFA) in 2000 in the class of Prof. Stefan Danailov. In 1997 she debuted with the role of Anna in "The Lower Depths" by Maxim Gorky in Ivan Vazov National Theatre. Among her other roles are: Harey in "Solaris" by Stanislaw Lem and Volange in "Quartet" by Heiner Muller in Theatre-Laboratory Sfumato, Majoa in "The Betrothal" by Maurice Maeterlinck in The Aleko Konstantinov State Satirical Theatre. On the stage of the National Theater, she has played Beatrice in "Decameron or Blood and Passion after Boccaccio" by Alexander Morfov, Chloe in "Arcadia" by Tom Stoppard, Salome in "Salome" by Oscar Wilde, Perdita in "The Winter’s Tale" by William Shakespeare, Julie in "Jake's Women" by Neil Simon, the Maid in "The Unapproachable" by Krzysztof Zanussi, Woman in the "Runaway Plane" by Kamen Donev, Adela in "The House of Bernarda Alba" by Federico Garcia Lorca, Rosette in "No Trifling with Love" by Alfred de Musset, Dona Elvira in "Don Juan" by Molière, Anna Petrovna in "Ivanov" and Anya in "The Cherry Orchard" by Anton Chekhov, Anna in "Thessaloniki Conspiracy" by Georgi Danailov, Gina Ekdal in "The Wild Duck" by Henrik Ibsen, Birdie in "The Little Foxes" by Lillian Hellman, Ghana Popatanasova in "The Observers" by Konstantin Iliev, Cleo in "Knight of The Holy Spirit" by Boyan Papazov, Katerina Ivanovna in "The Brothers Karamazov".
In 2000 she received the "Ivan Dimov" award for Young Theatrical Talents, and in 2018 she won the ASKEER Award for Best Supporting Actress for her performance in "The Little Foxes". In 2019 she was nominated for the Icarus Award for her role in "The Wild Duck".
During this season, on the stage of the Ivan Vazov National Theatre, you can watch Ana Papadopoulou in the following performances: "The Little Foxes," "The Wild Duck," "The Observers", "The Footnotes", "Some Girl(s)", "Pieces of a Woman" and "Nora".